Nicotine addiction management

 


Management on Nicotine Addiction -

Nicotine replacement therapy
Nicotine replacement therapy (NRT) works by making it easier to abstain from tobacco by partially replacing the nicotine previously obtained from tobacco. All of the commercially available forms of NRT increase the chances of successful smoking cessation. Overall, NRT increases the quit rate by 50-70%, and the increase appears to be independent of any additional support provided.

Types of NRT products on the market today include the following:
Transdermal nicotine patch
Nicotine nasal spray
Nicotine gum
Nicotine lozenge
Sublingual nicotine tablet
Nicotine inhaler

Non-nicotine pharmacotherapy
The medications bupropion and varenicline have demonstrated efficacy for smoking cessation.
Bupropion acts by alleviating some of the symptoms of nicotine withdrawal. Like NRT products, bupropion has been endorsed by the US Clinical Practice Guideline as a first-line therapy. Compared with placebo, bupropion approximately doubles smoking cessation rates, and it is equally effective for men and women.
Varenicline is a partial agonist that is selective for alpha-4, beta-2 nicotinic acetylcholine receptors (nAChRs). The drug helps smokers quit by preventing withdrawal symptoms while moderate levels of dopamine are maintained in the brain.
Some reviews have found that patients receiving varenicline are at an increased risk for serious adverse cardiovascular events. On the basis of study findings, extreme caution should be used when considering varenicline for patients with known cardiovascular problems.
Combination treatment with varenicline and bupropion may be more effective than single-drug therapy for smoking cessation in those smokers motivated to quit.
Location: Pune, Maharashtra, India

Comments

Post a Comment

Popular posts from this blog

Club-drugs

Image
  The main club drugs are: Flunitrazepam (roofies) GHB (liquid ecstasy) Ketamine (special K) LSD (acid) MDMA (ecstasy or molly) Methamphetamine (meth) Club drugs contain a combination of agents that affect your brain and central nervous system. All of them can lead you to make choices or do things you wouldn’t otherwise do. Stimulants make you excitable. They can cause you to feel open, aroused, and unafraid. Depressants slow your nervous system and affect your ability to react. Hallucinogens affect your ability to think, feel, judge, and act. They make it hard to know what’s real or not. They can cause you to forget periods of time. Methamphetamines are stimulants that cause excitement. They can make you hyper, anxious, or paranoid.
Read more

Neurological Complications of Alcohol Use

Image
  Neurological Complications of Alcohol Use Neurological Complications of Alcohol Use - 1. Alcoholic Neuropathy      a. Acute Alcoholic Neuropathy      b. Alcohol-related - Compressive Neuropathy - Excessive alcohol consumption is traditionally associated with ‘Saturday night palsy’, caused by compression of the radial nerve against the humerus for several hours.      c. Chronic Alcholic Neuropathy - The onset of symptoms is insidious and symmetric, predominantly sensory, in the form of dysesthesia, burning sensation and burning pain on the soles of the feet that later develops into cramp in the calves and the hands. Motor symptoms usually manifest later, and are characterised by muscle weakness and atrophy, especially in the distal muscles of the upper or lower limbs. Vegetative vascular and skin defects (sweaty, atrophic, glossy, almost hairless skin) with associated dysautonomia are also typical. 2. Withdrawl symptoms and delirium tremens - The manifestations of withdrawal syn
Read more

Happy-Dussehra

Image
  According to the Hindu calendar, the holy festival of Vijayadashami is observed on the tenth day of Shukla Paksha of Ashwin month. This festival is celebrated as the victory of truth over falsehood as Lord Ram defeated Ravana and his army in a long battle. It is believed that burning the effigy of Ravana, Meghnad and Kumbhakaran on this day destroys all evils. On the other hand, according to another mythology, there was a demon named Mahishasura, who was a great devotee of Brahma. He had pleased Brahmaji with his hard penance and obtained a boon that no deity or any human living on earth could kill him. After receiving the boon, he became extremely ruthless and arrogant and started creating terror in the universe. He started attacking the gods and defeated them in battle and started capturing their territory. Disturbed by the terror of Mahishasura, all the gods and goddesses came to the shelter of Brahma, Vishnu and Lord Shiva. Seeing all the gods and goddesses in trouble, Brahma, Vi
Read more